The inspiring story of Jack Hoffman, a young man whose courageous battle against brain cancer touched the lives of millions, came to a poignant end in January 2025. At the age of 19, Jack succumbed to the disease that he had valiantly fought for 14 years, leaving behind a legacy of hope, resilience, and a profound impact on pediatric brain cancer research. His journey began in 2011 with a devastating diagnosis, but it was also the start of a remarkable chapter filled with unexpected moments of joy, connection, and unwavering determination. His story intertwined with the University of Nebraska Cornhuskers football team, transforming him into a symbol of courage and inspiration for the entire community and beyond.
Jack’s connection with the Cornhuskers began when his father, Andy Hoffman, reached out to star running back Rex Burkhead. This connection blossomed into a deep bond, leading to a defining moment in Jack’s life. In 2013, during the fourth quarter of a Nebraska spring game, 7-year-old Jack, wearing a miniature Burkhead jersey, took a handoff and ran 69 yards for a touchdown, captivating the 60,000 fans in Memorial Stadium. “The Run,” as it became known, transcended the realm of sports, becoming a viral sensation that touched hearts across the globe. The video garnered millions of views on YouTube, propelling Jack into the national spotlight. This extraordinary moment led to a visit with then-President Barack Obama and culminated in Jack receiving the ESPY Award for “Best Moment in Sports.”
“The Run” became the catalyst for the creation of the Team Jack Foundation, spearheaded by Jack’s parents. This foundation emerged as a beacon of hope for children battling brain cancer, raising over $14 million for pediatric brain cancer research. Tragically, Jack’s father, Andy, also succumbed to an aggressive form of brain cancer, glioblastoma multiforme, in 2021 at the young age of 42, underscoring the devastating impact of this disease and further fueling the foundation’s mission. Despite the personal tragedies, the Hoffman family’s dedication to raising awareness and funding research remained unwavering.
Despite his ongoing battle with cancer, Jack lived his life to the fullest. He played high school football as a lineman, a testament to his resilience and determination. He furthered his education by enrolling at the University of Nebraska-Kearney in 2024, pursuing a degree in political science. He excelled academically, making the Dean’s List in his first semester, demonstrating his commitment to learning and personal growth. His presence on campus enriched the university community, inspiring fellow students and faculty alike. The university recognized his contributions and impact, highlighting his courageous spirit and his tireless efforts to raise awareness about childhood cancer.
Even as his health declined, Jack remained a symbol of hope and strength. In the summer of 2024, following a tumor resection surgery, pathology results revealed that his tumor had progressed to a high-grade glioma. However, this devastating news did not diminish his spirit. He remained connected to the community, continuing to inspire others with his courage and determination. He embraced life, cherishing the time he had with his family and friends. He continued to champion the cause of pediatric brain cancer research, ensuring that his legacy would live on in the fight against this devastating disease.
Jack Hoffman’s passing in January 2025 brought immense sadness to all who knew him and were inspired by his story. Tributes poured in from across the nation, reflecting the profound impact he had made. The University of Nebraska, the Cornhuskers football team, and Rex Burkhead, his longtime friend and supporter, all expressed their deep sorrow and celebrated his enduring legacy. Jack’s story serves as a powerful reminder of the importance of perseverance, hope, and the impact one individual can have in the face of adversity. His legacy continues through the Team Jack Foundation, which remains dedicated to advancing pediatric brain cancer research and providing support to families facing similar challenges. Jack’s life, though tragically cut short, will continue to inspire others to fight for a cure and to cherish every precious moment. He will be remembered not only for “The Run” but also for his unwavering spirit, his courageous battle, and his enduring legacy of hope.
